GEODON is a prescription medicine. It is used to treat acute manic or mixed episodes associated with bipolar disorder. GEODON is also used as maintenance treatment of bipolar disorder when added to lithium or valproate (Depakote®) and to treat schizophrenia. For full symptoms and diagnostic criteria, see Slevotra the DSM-IV-TR® (2000). GEODON may increase the risk of changes to your heart rhythm. In some cases these types of changes can be fatal though it is unknown whether this is the case with GEODON. It is important to talk to your doctor about this potential side effect, as your doctor may consider a different medicine first.
GEODON® (ziprasidone HCl) Capsules Indications
GEODON is a prescription medicine. It is used to treat acute manic or mixed episodes associated with bipolar disorder. GEODON is also used as maintenance treatment of bipolar disorder when added to lithium or valproate (Depakote®) and to treat schizophrenia. For full symptoms and diagnostic criteria, see the DSM-IV-TR® (2000). GEODON may increase the risk of changes to your heart rhythm. In some cases these types of changes can be fatal though it is unknown whether this is the case with GEODON. It is important to talk to your doctor about this potential side effect, as your doctor may consider a different medicine first.
GEODON Important Safety Information
GEODON may increase the risk of changes to your heart rhythm. You should not take GEODON if you have certain kinds of heart conditions that change your heart rhythm, a recent heart attack, heart failure, or take certain medicines known to change heart rhythm. It is important to talk to your doctor about this possible side effect. Call your doctor right away if you faint, pass out, or feel a change in your heartbeat.
If you experience a high fever, stiff muscles, shaking, confusion, sweating, or increased heart rate or blood pressure, tell your doctor right away. These can be signs of a rare but potentially fatal condition called neuroleptic malignant syndrome (NMS).
If you experience abnormal or uncontrollable facial or body movements, notify your doctor. These could be a sign of tardive dyskinesia (TD), a potentially permanent condition whose risk increases with the length of treatment, but which can also occur after brief periods at low doses.
If you have diabetes or have risk factors or symptoms of diabetes, your blood sugar should be monitored. Symptoms include excessive thirst, urination, appetite, and weakness. High blood sugar has been reported with GEODON and medicines like it. In some cases, extreme high blood sugar can lead to coma or death.
Tell your doctor if you are pregnant or intend to become pregnant. Breast feeding is not recommended.
If you experience a rash, lightheadedness upon standing, or seizures, tell your doctor. Also tell your doctor if you have thoughts of suicide.
Other risks may include decreases in white blood cells (which can be serious), trouble swallowing, high prolactin levels, and impairment in judgment or motor skills. Until you know how GEODON affects you, you should not drive or operate machinery.
Do not drink alcohol while taking GEODON. Avoid becoming overheated or dehydrated. Common side effects of GEODON include:
In short-term bipolar mania clinical studies, 4.9% of GEODON-treated patients gained significant weight (7% or more of body weight) vs 3.3% for placebo.
In a long-term bipolar maintenance clinical study, patients who tolerated GEODON plus lithium or valproate (Depakote) for 10-16 weeks were either continued on GEODON or switched to placebo for up to 6 months. During these 6 months, 5.6% of patients in both groups gained significant weight. These results do not include patients who did not complete the study.
In short-term schizophrenia clinical studies, 10% of GEODON-treated patients gained significant weight vs 4% for placebo.
GEODON® (ziprasidone HCl) Capsules Indications
GEODON is a prescription medicine. It is used to treat acute manic or mixed episodes associated with bipolar disorder. GEODON is also used as maintenance treatment of bipolar disorder when added to lithium or valproate (Depakote®) and to treat schizophrenia. For full symptoms and diagnostic criteria, see the DSM-IV-TR® (2000). GEODON may increase the risk of changes to your heart rhythm. In some cases these types of changes can be fatal though it is unknown whether this is the case with GEODON. It is important to talk to your doctor about this potential side effect, as your doctor may consider a different medicine first.
GEODON Important Safety Information
| Elderly patients with dementia-related psychosis (having lost touch with reality due to confusion and memory loss) treated with this type of medicine are at an increased risk of death, compared to placebo (sugar pill). GEODON is not approved for treating these patients. |
GEODON may increase the risk of changes to your heart rhythm. You should not take GEODON if you have certain kinds of heart conditions that change your heart rhythm, a recent heart attack, heart failure, or take certain medicines known to change heart rhythm. It is important to talk to your doctor about this possible side effect. Call your doctor right away if you faint, pass out, or feel a change in your heartbeat.
If you experience a high fever, stiff muscles, shaking, confusion, sweating, or increased heart rate or blood pressure, tell your doctor right away. These can be signs of a rare but potentially fatal condition called neuroleptic malignant syndrome (NMS).
If you experience abnormal or uncontrollable facial or body movements, notify your doctor. These could be a sign of tardive dyskinesia (TD), a potentially permanent condition whose risk increases with the length of treatment, but which can also occur after brief periods at low doses.
If you have diabetes or have risk factors or symptoms of diabetes, your blood sugar should be monitored. Symptoms include excessive thirst, urination, appetite, and weakness. High blood sugar has been reported with GEODON and medicines like it. In some cases, extreme high blood sugar can lead to coma or death.
Tell your doctor if you are pregnant or intend to become pregnant. Breast feeding is not recommended.
If you experience a rash, lightheadedness upon standing, or seizures, tell your doctor. Also tell your doctor if you have thoughts of suicide.
Other risks may include decreases in white blood cells (which can be serious), trouble swallowing, high prolactin levels, and impairment in judgment or motor skills. Until you know how GEODON affects you, you should not drive or operate machinery.
Do not drink alcohol while taking GEODON. Avoid becoming overheated or dehydrated. Common side effects of GEODON include:
|
|
In short-term bipolar mania clinical studies, 4.9% of GEODON-treated patients gained significant weight (7% or more of body weight) vs 3.3% for placebo.
In a long-term bipolar maintenance clinical study, patients who tolerated GEODON plus lithium or valproate (Depakote) for 10-16 weeks were either continued on GEODON or switched to placebo for up to 6 months. During these 6 months, 5.6% of patients in both groups gained significant weight. These results do not include patients who did not complete the study.
In short-term schizophrenia clinical studies, 10% of GEODON-treated patients gained significant weight vs 4% for placebo.
